iSAIRR is a synergistically integrated infrastructure that offers a broad spectrum of imaging modalities, techniques, and services for in vivo imaging of small animals and ex vivo imaging of tissue/organ specimens. Our goal is to provide University of Chicago investigators and external users with state of the art, quantitative multi-modality imaging technologies to advance in-vivo molecular and physiological research of a broad range of disease and cancer models, and to accelerate pre-clinical development of novel therapeutics and diagnostic tools. Currently, iSAIRR sub-cores feature magnetic resonance imaging and spectroscopy (MRIS); optical imaging (bioluminescence and fluorescence); positron emission tomography, single photon emission computed tomography, and computed tomography (PET/SPECT/CT).

      iSAIRR comprehensive services include:
    • Assistance with experimental design
    • Assisted and/or independent image acquisition
    • Veterinary support for all imaging modalities
    • Assistance with data processing and interpretation

    Potential internal and external users are encouraged to contact us to discuss their imaging needs.

    The Integrated Small Animal Imaging Research Resource is partially supported by funds from the University of Chicago Comprehensive Cancer Center from the National Cancer Institute.

    Acknowledgement of core facility contributions in publications is appreciated.

    Cancer Center members should cite the Cancer Center Support Grant (P30CA014599) when publishing any work assisted by this core facility.

    Sample language to acknowledge the core in publications: We thank The University of Chicago iSAIRR (RRID:SCR_017923), especially [staff name], for their assistance with [technique name].